About megatomi.com
About megatomi.com
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Our new Clear+ tissue clearing procedure is the sole technique that delipidates samples without any improve in morphology and with small effect on structural integrity.
Our turn-crucial SmartBatch+ procedure brings together electrophoretic tissue clearing and immunolabeling into one higher-throughput gadget.
Antibodies may well just take weeks to diffuse by way of only some millimeters of tissue, using a steep labeling gradient from area to core.
Megatome is suitable for accuracy: the blade vibrates at an increased frequency and larger amplitude selection than other microtomes, and features a exclusive deflection Command mechanism.
SE makes use of a rotational electrical industry to disperse highly electromobile molecules (including antibodies or surfactant micelles) through a porous sample with no detrimental electrically charged structures throughout the tissue. This allows two-4 day clearing of intact organs,
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Megatome is actually a novel microtome that allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue damage and data loss.
eFLASH is often a speedy tissue labeling technique that enables for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light-weight sheet microscope gives unparalleled resolution and acquisition velocity during intact tissue volumes, while its modular layout allows you to improve and personalize person parts.
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SHIELD avoids the variability of hydrogel embedding and the knowledge reduction from PFA preservation, protecting megatomi.com specimens for many rounds of processing.
Leverage the Very clear+ tissue clearing process, as well as eFLASH and patented stochastic electrotransport systems, to speedily clear and label entire organs. Vital highlights and functions include:
Our novel Defend tissue preservation technique kinds intramolecular bonds applying polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.